Name	Flags	Card.	Type	Description & Constraints
Observation	C	0..*	ObservationBase	Measurements and simple assertions inv-pharmacological-test-partOf-warning: Include a reference to MedicationAdministration in partOf when PharmacologicalTestActiveSubstanceInEyedrops is present.
partOf		0..*	Reference(https://larfuma.github.io/fhir-eyecare-ig/StructureDefinition-pupil-comparison)	Reference for Pharmacological Testing
code		1..1	CodeableConcept	Type of observation (code / type) Fixed Value: As shown
coding		1..1	Coding	Code defined by a terminology system Fixed Value: (complex)
system		1..1	uri	Identity of the terminology system Fixed Value: http://loinc.org
code		1..1	code	Symbol in syntax defined by the system Fixed Value: LP73214-6
display		1..1	string	Representation defined by the system Fixed Value: Pupil diameter
value[x]		1..1	Quantity	Actual result
unit		0..1	string	mm Fixed Value: mm
system		0..1	uri	System that defines coded unit form Fixed Value: http://unitsofmeasure.org
code		0..1	code	Coded form of the unit Fixed Value: mm
note		0..0
bodySite		1..1	CodeableConcept	​Observed body part Binding: https://larfuma.github.io/fhir-eyecare-ig/ValueSet-right-left-both-eyes (required)
coding		0..*	Coding	Code defined by a terminology system Binding: ValueSet-right-left-eyes (required): Valueset constrained to either the right or left eye
Slices for component		0..*	BackboneElement	Component results Slice: Unordered, Open by value:code
component:RoomBrightness		0..1	BackboneElement	Component results
code		1..1	CodeableConcept	Type of component observation (code / type) Fixed Value: As shown
coding		1..1	Coding	Code defined by a terminology system Fixed Value: (complex)
system		1..1	uri	Identity of the terminology system Fixed Value: http://loinc.org
code		1..1	code	Symbol in syntax defined by the system Fixed Value: LP429645-7
display		1..1	string	Representation defined by the system Fixed Value: Room brightness level during testing
Slices for value[x]		0..1		Actual component result Slice: Unordered, Open by type:$this
valueQuantity			Quantity
valueCodeableConcept			CodeableConcept
value[x]:valueCodeableConcept		0..1	CodeableConcept	Actual component result Binding: Room Brightness Levels (preferred): Room Brightness levels
value[x]:valueQuantity		0..1	Quantity	Luminance
unit		0..1	string	Room Illuminance Fixed Value: lux
system		0..1	uri	System that defines coded unit form Fixed Value: http://unitsofmeasure.org
code		0..1	code	Lux Fixed Value: lx
interpretation		0..0
referenceRange		0..0
component:PupilLuminance		0..1	BackboneElement	Component results
code		1..1	CodeableConcept	Type of component observation (code / type) Fixed Value: As shown
coding		1..1	Coding	Code defined by a terminology system Fixed Value: (complex)
system		1..1	uri	Identity of the terminology system Fixed Value: http://snomed.info/sct
code		1..1	code	Symbol in syntax defined by the system Fixed Value: 27073006
display		1..1	string	Representation defined by the system Fixed Value: Luminance
value[x]		0..1	Quantity	Actual component result
unit		0..1	string	candela per square meter Fixed Value: cd/m2
system		0..1	uri	System that defines coded unit form Fixed Value: http://unitsofmeasure.org
code		0..1	code	Coded form of the unit Fixed Value: cd/m2
interpretation		0..0
referenceRange		0..0
component:PharmacologicalTestDurationSinceAdministration		0..1	BackboneElement	Component results
value[x]		0..1	Quantity	Actual component result
unit		0..1	string	Unit representation Fixed Value: minutes
system		0..1	uri	System that defines coded unit form Fixed Value: unitsofmeasure.org
code		0..1	code	Coded form of the unit Fixed Value: min
component:PharmacologicalTestActiveSubstanceInEyedrops		0..1	BackboneElement	Component results
code		1..1	CodeableConcept	Type of component observation (code / type) Fixed Value: As shown
coding		1..1	Coding	Code defined by a terminology system Fixed Value: (complex)
system		1..1	uri	Identity of the terminology system Fixed Value: http://snomed.info/sct
code		1..1	code	Symbol in syntax defined by the system Fixed Value: 410942007
display		1..1	string	Representation defined by the system Fixed Value: Drug or medicament (substance)
value[x]		0..1		Actual component result Binding: Pupil Testing Active Substances (preferred): Valueset of active substances typically used in pharmacological pupil testing
valueCodeableConcept			CodeableConcept
valueString			string
component:PharmacologicalTestEyedropConcentration		0..1	BackboneElement	Component results
code		1..1	CodeableConcept	Type of component observation (code / type) Fixed Value: As shown
coding		1..1	Coding	Code defined by a terminology system Fixed Value: (complex)
system		1..1	uri	Identity of the terminology system Fixed Value: http://snomed.info/sct
code		1..1	code	Symbol in syntax defined by the system Fixed Value: 702942001
display		1..1	string	Representation defined by the system Fixed Value: Concentration
value[x]		0..1	Quantity	Actual component result
Documentation for this format

Terminology Bindings (Differential)

Path	Conformance	ValueSet	URI
Observation.bodySite	required	​https://larfuma.github.io/fhir-eyecare-ig/ValueSet-right-left-both-eyes https://larfuma.github.io/fhir-eyecare-ig/ValueSet-right-left-both-eyes
Observation.bodySite.coding	required	ValueSet-right-left-eyes https://larfuma.github.io/fhir-eyecare-ig/ValueSet-right-left-eyes.html from this IG
Observation.component:RoomBrightness.value[x]:valueCodeableConcept	preferred	RoomBrightnessLevels https://larfuma.github.io/fhir-eyecare-ig/ValueSet-room-brightness-levels from this IG
Observation.component:PharmacologicalTestActiveSubstanceInEyedrops.value[x]	preferred	PupiTestingActiveSubstances https://larfuma.github.io/fhir-eyecare-ig/ValueSet-pupi-testing-active-substances from this IG

Constraints

Id	Grade	Path(s)	Details	Requirements
inv-pharmacological-test-partOf-warning	warning	Observation	Include a reference to MedicationAdministration in partOf when PharmacologicalTestActiveSubstanceInEyedrops is present. : component.where(code.coding.code = '410942007').exists() implies partOf.exists()

Name	Flags	Card.	Type	Description & Constraints
Observation	C	0..*	ObservationBase	Measurements and simple assertions dom-2: If the resource is contained in another resource, it SHALL NOT contain nested Resources dom-3: If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource dom-4: If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated dom-5: If a resource is contained in another resource, it SHALL NOT have a security label dom-6: A resource should have narrative for robust management obs-6: dataAbsentReason SHALL only be present if Observation.value[x] is not present obs-7: If Observation.code is the same as an Observation.component.code then the value element associated with the code SHALL NOT be present inv-pharmacological-test-partOf-warning: Include a reference to MedicationAdministration in partOf when PharmacologicalTestActiveSubstanceInEyedrops is present.
implicitRules	?!Σ	0..1	uri	A set of rules under which this content was created ele-1: All FHIR elements must have a @value or children
modifierExtension	?!	0..*	Extension	Extensions that cannot be ignored ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
partOf	Σ	0..*	Reference(https://larfuma.github.io/fhir-eyecare-ig/StructureDefinition-pupil-comparison)	Reference for Pharmacological Testing ele-1: All FHIR elements must have a @value or children
status	?!SΣ	1..1	code	final | amended Binding: Observation Status (required): Reduced status set ele-1: All FHIR elements must have a @value or children
Slices for category	S	1..*	CodeableConcept	Classification of type of observation Slice: Unordered, Open by value:coding.code, value:coding.system Binding: ObservationCategoryCodes (preferred): Codes for high level observation categories. ele-1: All FHIR elements must have a @value or children
category:ophthalCategory		1..1	CodeableConcept	Classification of type of observation Binding: ObservationCategoryCodes (preferred): Codes for high level observation categories. ele-1: All FHIR elements must have a @value or children
coding	Σ	1..1	Coding	Code defined by a terminology system ele-1: All FHIR elements must have a @value or children
system	Σ	1..1	uri	Identity of the terminology system ele-1: All FHIR elements must have a @value or children Fixed Value: http://terminology.hl7.org/CodeSystem/observation-category
code	Σ	1..1	code	Symbol in syntax defined by the system ele-1: All FHIR elements must have a @value or children Fixed Value: exam
code	SΣ	1..1	CodeableConcept	Type of observation (code / type) Binding: LOINCCodes (example): Codes identifying names of simple observations. ele-1: All FHIR elements must have a @value or children Fixed Value: As shown
id		0..0	string	Unique id for inter-element referencing
extension		0..0	Extension	Additional content defined by implementations
coding		1..1	Coding	Code defined by a terminology system Fixed Value: (complex)
id		0..0	string	Unique id for inter-element referencing
extension		0..0	Extension	Additional content defined by implementations
system		1..1	uri	Identity of the terminology system Fixed Value: http://loinc.org
version		0..0	string	Version of the system - if relevant
code		1..1	code	Symbol in syntax defined by the system Fixed Value: LP73214-6
display		1..1	string	Representation defined by the system Fixed Value: Pupil diameter
userSelected		0..0	boolean	If this coding was chosen directly by the user
text		0..0	string	Plain text representation of the concept
subject	SΣ	1..1	Reference(Patient)	Who and/or what the observation is about ele-1: All FHIR elements must have a @value or children
value[x]	ΣC	1..1	Quantity	Actual result ele-1: All FHIR elements must have a @value or children
comparator	?!Σ	0..1	code	< | <= | >= | > - how to understand the value Binding: QuantityComparator (required): How the Quantity should be understood and represented. ele-1: All FHIR elements must have a @value or children
unit	Σ	0..1	string	mm ele-1: All FHIR elements must have a @value or children Fixed Value: mm
system	ΣC	0..1	uri	System that defines coded unit form ele-1: All FHIR elements must have a @value or children Fixed Value: http://unitsofmeasure.org
code	Σ	0..1	code	Coded form of the unit ele-1: All FHIR elements must have a @value or children Fixed Value: mm
bodySite	S	1..1	CodeableConcept	​Observed body part Binding: https://larfuma.github.io/fhir-eyecare-ig/ValueSet-right-left-both-eyes (required) ele-1: All FHIR elements must have a @value or children
Slices for extension		0..1	Extension	Extension Slice: Unordered, Open by value:url ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
bodySiteEye	S	0..*	(Complex)	Target anatomic location or structure URL: http://hl7.org/fhir/StructureDefinition/bodySite ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
extension		0..0
url		1..1	uri	"http://hl7.org/fhir/StructureDefinition/bodySite"
value[x]	S	1..1	Reference(BodyStructure | Ocular anatomical location)	Value of extension ele-1: All FHIR elements must have a @value or children
coding	Σ	0..*	Coding	Code defined by a terminology system Binding: ValueSet-right-left-eyes (required): Valueset constrained to either the right or left eye ele-1: All FHIR elements must have a @value or children
Slices for component	Σ	0..*	BackboneElement	Component results Slice: Unordered, Open by value:code ele-1: All FHIR elements must have a @value or children
component:All Slices				Content/Rules for all slices
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
code	Σ	1..1	CodeableConcept	Type of component observation (code / type) Binding: LOINCCodes (example): Codes identifying names of simple observations. ele-1: All FHIR elements must have a @value or children
component:RoomBrightness	Σ	0..1	BackboneElement	Component results ele-1: All FHIR elements must have a @value or children
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
code	Σ	1..1	CodeableConcept	Type of component observation (code / type) Binding: LOINCCodes (example): Codes identifying names of simple observations. ele-1: All FHIR elements must have a @value or children Fixed Value: As shown
id		0..0	string	Unique id for inter-element referencing
extension		0..0	Extension	Additional content defined by implementations
coding		1..1	Coding	Code defined by a terminology system Fixed Value: (complex)
id		0..0	string	Unique id for inter-element referencing
extension		0..0	Extension	Additional content defined by implementations
system		1..1	uri	Identity of the terminology system Fixed Value: http://loinc.org
version		0..0	string	Version of the system - if relevant
code		1..1	code	Symbol in syntax defined by the system Fixed Value: LP429645-7
display		1..1	string	Representation defined by the system Fixed Value: Room brightness level during testing
userSelected		0..0	boolean	If this coding was chosen directly by the user
text		0..0	string	Plain text representation of the concept
Slices for value[x]	Σ	0..1		Actual component result Slice: Unordered, Closed by type:$this ele-1: All FHIR elements must have a @value or children
valueQuantity			Quantity
valueCodeableConcept			CodeableConcept
value[x]:valueCodeableConcept	Σ	0..1	CodeableConcept	Actual component result Binding: Room Brightness Levels (preferred): Room Brightness levels ele-1: All FHIR elements must have a @value or children
value[x]:valueQuantity	Σ	0..1	Quantity	Luminance ele-1: All FHIR elements must have a @value or children
comparator	?!Σ	0..1	code	< | <= | >= | > - how to understand the value Binding: QuantityComparator (required): How the Quantity should be understood and represented. ele-1: All FHIR elements must have a @value or children
unit	Σ	0..1	string	Room Illuminance ele-1: All FHIR elements must have a @value or children Fixed Value: lux
system	ΣC	0..1	uri	System that defines coded unit form ele-1: All FHIR elements must have a @value or children Fixed Value: http://unitsofmeasure.org
code	Σ	0..1	code	Lux ele-1: All FHIR elements must have a @value or children Fixed Value: lx
component:PupilLuminance	Σ	0..1	BackboneElement	Component results ele-1: All FHIR elements must have a @value or children
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
code	Σ	1..1	CodeableConcept	Type of component observation (code / type) Binding: LOINCCodes (example): Codes identifying names of simple observations. ele-1: All FHIR elements must have a @value or children Fixed Value: As shown
id		0..0	string	Unique id for inter-element referencing
extension		0..0	Extension	Additional content defined by implementations
coding		1..1	Coding	Code defined by a terminology system Fixed Value: (complex)
id		0..0	string	Unique id for inter-element referencing
extension		0..0	Extension	Additional content defined by implementations
system		1..1	uri	Identity of the terminology system Fixed Value: http://snomed.info/sct
version		0..0	string	Version of the system - if relevant
code		1..1	code	Symbol in syntax defined by the system Fixed Value: 27073006
display		1..1	string	Representation defined by the system Fixed Value: Luminance
userSelected		0..0	boolean	If this coding was chosen directly by the user
text		0..0	string	Plain text representation of the concept
value[x]	Σ	0..1	Quantity	Actual component result ele-1: All FHIR elements must have a @value or children
comparator	?!Σ	0..1	code	< | <= | >= | > - how to understand the value Binding: QuantityComparator (required): How the Quantity should be understood and represented. ele-1: All FHIR elements must have a @value or children
unit	Σ	0..1	string	candela per square meter ele-1: All FHIR elements must have a @value or children Fixed Value: cd/m2
system	ΣC	0..1	uri	System that defines coded unit form ele-1: All FHIR elements must have a @value or children Fixed Value: http://unitsofmeasure.org
code	Σ	0..1	code	Coded form of the unit ele-1: All FHIR elements must have a @value or children Fixed Value: cd/m2
component:PharmacologicalTestDurationSinceAdministration	Σ	0..1	BackboneElement	Component results ele-1: All FHIR elements must have a @value or children
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
code	Σ	1..1	CodeableConcept	Type of component observation (code / type) Binding: LOINCCodes (example): Codes identifying names of simple observations. ele-1: All FHIR elements must have a @value or children
value[x]	Σ	0..1	Quantity	Actual component result ele-1: All FHIR elements must have a @value or children
comparator	?!Σ	0..1	code	< | <= | >= | > - how to understand the value Binding: QuantityComparator (required): How the Quantity should be understood and represented. ele-1: All FHIR elements must have a @value or children
unit	Σ	0..1	string	Unit representation ele-1: All FHIR elements must have a @value or children Fixed Value: minutes
system	ΣC	0..1	uri	System that defines coded unit form ele-1: All FHIR elements must have a @value or children Fixed Value: unitsofmeasure.org
code	Σ	0..1	code	Coded form of the unit ele-1: All FHIR elements must have a @value or children Fixed Value: min
component:PharmacologicalTestActiveSubstanceInEyedrops	Σ	0..1	BackboneElement	Component results ele-1: All FHIR elements must have a @value or children
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
code	Σ	1..1	CodeableConcept	Type of component observation (code / type) Binding: LOINCCodes (example): Codes identifying names of simple observations. ele-1: All FHIR elements must have a @value or children Fixed Value: As shown
id		0..0	string	Unique id for inter-element referencing
extension		0..0	Extension	Additional content defined by implementations
coding		1..1	Coding	Code defined by a terminology system Fixed Value: (complex)
id		0..0	string	Unique id for inter-element referencing
extension		0..0	Extension	Additional content defined by implementations
system		1..1	uri	Identity of the terminology system Fixed Value: http://snomed.info/sct
version		0..0	string	Version of the system - if relevant
code		1..1	code	Symbol in syntax defined by the system Fixed Value: 410942007
display		1..1	string	Representation defined by the system Fixed Value: Drug or medicament (substance)
userSelected		0..0	boolean	If this coding was chosen directly by the user
text		0..0	string	Plain text representation of the concept
value[x]	Σ	0..1		Actual component result Binding: Pupil Testing Active Substances (preferred): Valueset of active substances typically used in pharmacological pupil testing ele-1: All FHIR elements must have a @value or children
valueCodeableConcept			CodeableConcept
valueString			string
component:PharmacologicalTestEyedropConcentration	Σ	0..1	BackboneElement	Component results ele-1: All FHIR elements must have a @value or children
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
code	Σ	1..1	CodeableConcept	Type of component observation (code / type) Binding: LOINCCodes (example): Codes identifying names of simple observations. ele-1: All FHIR elements must have a @value or children Fixed Value: As shown
id		0..0	string	Unique id for inter-element referencing
extension		0..0	Extension	Additional content defined by implementations
coding		1..1	Coding	Code defined by a terminology system Fixed Value: (complex)
id		0..0	string	Unique id for inter-element referencing
extension		0..0	Extension	Additional content defined by implementations
system		1..1	uri	Identity of the terminology system Fixed Value: http://snomed.info/sct
version		0..0	string	Version of the system - if relevant
code		1..1	code	Symbol in syntax defined by the system Fixed Value: 702942001
display		1..1	string	Representation defined by the system Fixed Value: Concentration
userSelected		0..0	boolean	If this coding was chosen directly by the user
text		0..0	string	Plain text representation of the concept
value[x]	Σ	0..1	Quantity	Actual component result ele-1: All FHIR elements must have a @value or children
Documentation for this format

Terminology Bindings

Path	Conformance	ValueSet / Code	URI
Observation.status	required	ObservationStatus http://terminology.hl7.org/uv/eyecare/ValueSet/observation-final-status from this IG
Observation.category	preferred	ObservationCategoryCodes http://hl7.org/fhir/ValueSet/observation-category from the FHIR Standard
Observation.category:ophthalCategory	preferred	ObservationCategoryCodes http://hl7.org/fhir/ValueSet/observation-category from the FHIR Standard
Observation.code	example	Fixed Value: LOINC Code LP73214-6("Pupil diameter") http://hl7.org/fhir/ValueSet/observation-codes from the FHIR Standard
Observation.value[x].comparator	required	QuantityComparator http://hl7.org/fhir/ValueSet/quantity-comparator|4.0.1 from the FHIR Standard
Observation.bodySite	required	​https://larfuma.github.io/fhir-eyecare-ig/ValueSet-right-left-both-eyes https://larfuma.github.io/fhir-eyecare-ig/ValueSet-right-left-both-eyes
Observation.bodySite.coding	required	ValueSet-right-left-eyes https://larfuma.github.io/fhir-eyecare-ig/ValueSet-right-left-eyes.html from this IG
Observation.component.code	example	LOINCCodes (a valid code from LOINC) http://hl7.org/fhir/ValueSet/observation-codes from the FHIR Standard
Observation.component:RoomBrightness.code	example	Fixed Value: LOINC Code LP429645-7("Room brightness level during testing") http://hl7.org/fhir/ValueSet/observation-codes from the FHIR Standard
Observation.component:RoomBrightness.value[x]:valueCodeableConcept	preferred	RoomBrightnessLevels https://larfuma.github.io/fhir-eyecare-ig/ValueSet-room-brightness-levels from this IG
Observation.component:RoomBrightness.value[x]:valueQuantity.comparator	required	QuantityComparator http://hl7.org/fhir/ValueSet/quantity-comparator|4.0.1 from the FHIR Standard
Observation.component:PupilLuminance.code	example	Fixed Value: SNOMED-CT Code 27073006("Luminance") http://hl7.org/fhir/ValueSet/observation-codes from the FHIR Standard
Observation.component:PupilLuminance.value[x].comparator	required	QuantityComparator http://hl7.org/fhir/ValueSet/quantity-comparator|4.0.1 from the FHIR Standard
Observation.component:PharmacologicalTestDurationSinceAdministration.code	example	LOINCCodes (a valid code from LOINC) http://hl7.org/fhir/ValueSet/observation-codes from the FHIR Standard
Observation.component:PharmacologicalTestDurationSinceAdministration.value[x].comparator	required	QuantityComparator http://hl7.org/fhir/ValueSet/quantity-comparator|4.0.1 from the FHIR Standard
Observation.component:PharmacologicalTestActiveSubstanceInEyedrops.code	example	Fixed Value: SNOMED-CT Code 410942007("Drug or medicament (substance)") http://hl7.org/fhir/ValueSet/observation-codes from the FHIR Standard
Observation.component:PharmacologicalTestActiveSubstanceInEyedrops.value[x]	preferred	PupiTestingActiveSubstances https://larfuma.github.io/fhir-eyecare-ig/ValueSet-pupi-testing-active-substances from this IG
Observation.component:PharmacologicalTestEyedropConcentration.code	example	Fixed Value: SNOMED-CT Code 702942001("Concentration") http://hl7.org/fhir/ValueSet/observation-codes from the FHIR Standard

Constraints

Id	Grade	Path(s)	Details	Requirements
dom-2	error	Observation	If the resource is contained in another resource, it SHALL NOT contain nested Resources : contained.contained.empty()
dom-3	error	Observation	If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource : contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()
dom-4	error	Observation	If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated : contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()
dom-5	error	Observation	If a resource is contained in another resource, it SHALL NOT have a security label : contained.meta.security.empty()
dom-6	best practice	Observation	A resource should have narrative for robust management : text.`div`.exists()
ele-1	error	**ALL** elements	All FHIR elements must have a @value or children : hasValue() or (children().count() > id.count())
ext-1	error	**ALL** extensions	Must have either extensions or value[x], not both : extension.exists() != value.exists()
inv-pharmacological-test-partOf-warning	warning	Observation	Include a reference to MedicationAdministration in partOf when PharmacologicalTestActiveSubstanceInEyedrops is present. : component.where(code.coding.code = '410942007').exists() implies partOf.exists()
obs-6	error	Observation	dataAbsentReason SHALL only be present if Observation.value[x] is not present : dataAbsentReason.empty() or value.empty()
obs-7	error	Observation	If Observation.code is the same as an Observation.component.code then the value element associated with the code SHALL NOT be present : value.empty() or component.code.where(coding.intersect(%resource.code.coding).exists()).empty()

Name	Flags	Card.	Type	Description & Constraints
Observation	C	0..*	ObservationBase	Measurements and simple assertions obs-6: dataAbsentReason SHALL only be present if Observation.value[x] is not present obs-7: If Observation.code is the same as an Observation.component.code then the value element associated with the code SHALL NOT be present inv-pharmacological-test-partOf-warning: Include a reference to MedicationAdministration in partOf when PharmacologicalTestActiveSubstanceInEyedrops is present.
id	Σ	0..1	id	Logical id of this artifact
meta	Σ	0..1	Meta	Metadata about the resource
implicitRules	?!Σ	0..1	uri	A set of rules under which this content was created
language		0..1	code	Language of the resource content Binding: CommonLanguages (preferred): A human language. Additional Bindings Purpose AllLanguages Max Binding
text		0..1	Narrative	Text summary of the resource, for human interpretation
contained		0..*	Resource	Contained, inline Resources
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!	0..*	Extension	Extensions that cannot be ignored
identifier	Σ	0..*	Identifier	Business Identifier for observation
basedOn	Σ	0..*	Reference(CarePlan | DeviceRequest | ImmunizationRecommendation | MedicationRequest | NutritionOrder | ServiceRequest)	Fulfills plan, proposal or order
partOf	Σ	0..*	Reference(https://larfuma.github.io/fhir-eyecare-ig/StructureDefinition-pupil-comparison)	Reference for Pharmacological Testing
status	?!SΣ	1..1	code	final | amended Binding: Observation Status (required): Reduced status set
Slices for category	S	1..*	CodeableConcept	Classification of type of observation Slice: Unordered, Open by value:coding.code, value:coding.system Binding: ObservationCategoryCodes (preferred): Codes for high level observation categories.
category:ophthalCategory		1..1	CodeableConcept	Classification of type of observation Binding: ObservationCategoryCodes (preferred): Codes for high level observation categories.
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
coding	Σ	1..1	Coding	Code defined by a terminology system
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
system	Σ	1..1	uri	Identity of the terminology system Fixed Value: http://terminology.hl7.org/CodeSystem/observation-category
version	Σ	0..1	string	Version of the system - if relevant
code	Σ	1..1	code	Symbol in syntax defined by the system Fixed Value: exam
display	Σ	0..1	string	Representation defined by the system
userSelected	Σ	0..1	boolean	If this coding was chosen directly by the user
text	Σ	0..1	string	Plain text representation of the concept
code	SΣ	1..1	CodeableConcept	Type of observation (code / type) Binding: LOINCCodes (example): Codes identifying names of simple observations. Fixed Value: As shown
id		0..0	string	Unique id for inter-element referencing
extension		0..0	Extension	Additional content defined by implementations
coding		1..1	Coding	Code defined by a terminology system Fixed Value: (complex)
id		0..0	string	Unique id for inter-element referencing
extension		0..0	Extension	Additional content defined by implementations
system		1..1	uri	Identity of the terminology system Fixed Value: http://loinc.org
version		0..0	string	Version of the system - if relevant
code		1..1	code	Symbol in syntax defined by the system Fixed Value: LP73214-6
display		1..1	string	Representation defined by the system Fixed Value: Pupil diameter
userSelected		0..0	boolean	If this coding was chosen directly by the user
text		0..0	string	Plain text representation of the concept
subject	SΣ	1..1	Reference(Patient)	Who and/or what the observation is about
focus	Σ	0..*	Reference(Resource)	What the observation is about, when it is not about the subject of record
encounter	Σ	0..1	Reference(Encounter)	Healthcare event during which this observation is made
effective[x]	Σ	0..1		Clinically relevant time/time-period for observation
effectiveDateTime			dateTime
effectivePeriod			Period
effectiveTiming			Timing
effectiveInstant			instant
issued	Σ	0..1	instant	Date/Time this version was made available
performer	Σ	0..*	Reference(Practitioner | PractitionerRole | Organization | CareTeam | Patient | RelatedPerson)	Who is responsible for the observation
value[x]	ΣC	1..1	Quantity	Actual result
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
value	Σ	0..1	decimal	Numerical value (with implicit precision)
comparator	?!Σ	0..1	code	< | <= | >= | > - how to understand the value Binding: QuantityComparator (required): How the Quantity should be understood and represented.
unit	Σ	0..1	string	mm Fixed Value: mm
system	ΣC	0..1	uri	System that defines coded unit form Fixed Value: http://unitsofmeasure.org
code	Σ	0..1	code	Coded form of the unit Fixed Value: mm
dataAbsentReason	C	0..1	CodeableConcept	Why the result is missing Binding: DataAbsentReason (extensible): Codes specifying why the result (Observation.value[x]) is missing.
interpretation		0..*	CodeableConcept	High, low, normal, etc. Binding: ObservationInterpretationCodes (extensible): Codes identifying interpretations of observations.
bodySite	S	1..1	CodeableConcept	​Observed body part Binding: https://larfuma.github.io/fhir-eyecare-ig/ValueSet-right-left-both-eyes (required)
id		0..1	string	Unique id for inter-element referencing
Slices for extension		0..1	Extension	Extension Slice: Unordered, Open by value:url
bodySiteEye	S	0..*	(Complex)	Target anatomic location or structure URL: http://hl7.org/fhir/StructureDefinition/bodySite
id		0..1	id	Unique id for inter-element referencing
extension		0..0
url		1..1	uri	"http://hl7.org/fhir/StructureDefinition/bodySite"
value[x]	S	1..1	Reference(BodyStructure | Ocular anatomical location)	Value of extension
coding	Σ	0..*	Coding	Code defined by a terminology system Binding: ValueSet-right-left-eyes (required): Valueset constrained to either the right or left eye
text	Σ	0..1	string	Plain text representation of the concept
method		0..1	CodeableConcept	How it was done Binding: ObservationMethods (example): Methods for simple observations.
specimen		0..1	Reference(Specimen)	Specimen used for this observation
device		0..1	Reference(Device | DeviceMetric)	(Measurement) Device
referenceRange	C	0..*	BackboneElement	Provides guide for interpretation obs-3: Must have at least a low or a high or text
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
low	C	0..1	SimpleQuantity	Low Range, if relevant
high	C	0..1	SimpleQuantity	High Range, if relevant
type		0..1	CodeableConcept	Reference range qualifier Binding: ObservationReferenceRangeMeaningCodes (preferred): Code for the meaning of a reference range.
appliesTo		0..*	CodeableConcept	Reference range population Binding: ObservationReferenceRangeAppliesToCodes (example): Codes identifying the population the reference range applies to.
age		0..1	Range	Applicable age range, if relevant
text		0..1	string	Text based reference range in an observation
hasMember	Σ	0..*	Reference(Observation | QuestionnaireResponse | MolecularSequence)	Related resource that belongs to the Observation group
derivedFrom	Σ	0..*	Reference(DocumentReference | ImagingStudy | Media | QuestionnaireResponse | Observation | MolecularSequence)	Related measurements the observation is made from
Slices for component	Σ	0..*	BackboneElement	Component results Slice: Unordered, Open by value:code
component:All Slices				Content/Rules for all slices
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
code	Σ	1..1	CodeableConcept	Type of component observation (code / type) Binding: LOINCCodes (example): Codes identifying names of simple observations.
value[x]	Σ	0..1		Actual component result
valueQuantity			Quantity
valueCodeableConcept			CodeableConcept
valueString			string
valueBoolean			boolean
valueInteger			integer
valueRange			Range
valueRatio			Ratio
valueSampledData			SampledData
valueTime			time
valueDateTime			dateTime
valuePeriod			Period
dataAbsentReason	C	0..1	CodeableConcept	Why the component result is missing Binding: DataAbsentReason (extensible): Codes specifying why the result (Observation.value[x]) is missing.
interpretation		0..*	CodeableConcept	High, low, normal, etc. Binding: ObservationInterpretationCodes (extensible): Codes identifying interpretations of observations.
referenceRange		0..*	See referenceRange (Observation)	Provides guide for interpretation of component result
component:RoomBrightness	Σ	0..1	BackboneElement	Component results
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
code	Σ	1..1	CodeableConcept	Type of component observation (code / type) Binding: LOINCCodes (example): Codes identifying names of simple observations. Fixed Value: As shown
id		0..0	string	Unique id for inter-element referencing
extension		0..0	Extension	Additional content defined by implementations
coding		1..1	Coding	Code defined by a terminology system Fixed Value: (complex)
id		0..0	string	Unique id for inter-element referencing
extension		0..0	Extension	Additional content defined by implementations
system		1..1	uri	Identity of the terminology system Fixed Value: http://loinc.org
version		0..0	string	Version of the system - if relevant
code		1..1	code	Symbol in syntax defined by the system Fixed Value: LP429645-7
display		1..1	string	Representation defined by the system Fixed Value: Room brightness level during testing
userSelected		0..0	boolean	If this coding was chosen directly by the user
text		0..0	string	Plain text representation of the concept
Slices for value[x]	Σ	0..1		Actual component result Slice: Unordered, Closed by type:$this
valueQuantity			Quantity
valueCodeableConcept			CodeableConcept
value[x]:valueCodeableConcept	Σ	0..1	CodeableConcept	Actual component result Binding: Room Brightness Levels (preferred): Room Brightness levels
value[x]:valueQuantity	Σ	0..1	Quantity	Luminance
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
value	Σ	0..1	decimal	Numerical value (with implicit precision)
comparator	?!Σ	0..1	code	< | <= | >= | > - how to understand the value Binding: QuantityComparator (required): How the Quantity should be understood and represented.
unit	Σ	0..1	string	Room Illuminance Fixed Value: lux
system	ΣC	0..1	uri	System that defines coded unit form Fixed Value: http://unitsofmeasure.org
code	Σ	0..1	code	Lux Fixed Value: lx
dataAbsentReason	C	0..1	CodeableConcept	Why the component result is missing Binding: DataAbsentReason (extensible): Codes specifying why the result (Observation.value[x]) is missing.
component:PupilLuminance	Σ	0..1	BackboneElement	Component results
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
code	Σ	1..1	CodeableConcept	Type of component observation (code / type) Binding: LOINCCodes (example): Codes identifying names of simple observations. Fixed Value: As shown
id		0..0	string	Unique id for inter-element referencing
extension		0..0	Extension	Additional content defined by implementations
coding		1..1	Coding	Code defined by a terminology system Fixed Value: (complex)
id		0..0	string	Unique id for inter-element referencing
extension		0..0	Extension	Additional content defined by implementations
system		1..1	uri	Identity of the terminology system Fixed Value: http://snomed.info/sct
version		0..0	string	Version of the system - if relevant
code		1..1	code	Symbol in syntax defined by the system Fixed Value: 27073006
display		1..1	string	Representation defined by the system Fixed Value: Luminance
userSelected		0..0	boolean	If this coding was chosen directly by the user
text		0..0	string	Plain text representation of the concept
value[x]	Σ	0..1	Quantity	Actual component result
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
value	Σ	0..1	decimal	Numerical value (with implicit precision)
comparator	?!Σ	0..1	code	< | <= | >= | > - how to understand the value Binding: QuantityComparator (required): How the Quantity should be understood and represented.
unit	Σ	0..1	string	candela per square meter Fixed Value: cd/m2
system	ΣC	0..1	uri	System that defines coded unit form Fixed Value: http://unitsofmeasure.org
code	Σ	0..1	code	Coded form of the unit Fixed Value: cd/m2
dataAbsentReason	C	0..1	CodeableConcept	Why the component result is missing Binding: DataAbsentReason (extensible): Codes specifying why the result (Observation.value[x]) is missing.
component:PharmacologicalTestDurationSinceAdministration	Σ	0..1	BackboneElement	Component results
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
code	Σ	1..1	CodeableConcept	Type of component observation (code / type) Binding: LOINCCodes (example): Codes identifying names of simple observations.
value[x]	Σ	0..1	Quantity	Actual component result
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
value	Σ	0..1	decimal	Numerical value (with implicit precision)
comparator	?!Σ	0..1	code	< | <= | >= | > - how to understand the value Binding: QuantityComparator (required): How the Quantity should be understood and represented.
unit	Σ	0..1	string	Unit representation Fixed Value: minutes
system	ΣC	0..1	uri	System that defines coded unit form Fixed Value: unitsofmeasure.org
code	Σ	0..1	code	Coded form of the unit Fixed Value: min
dataAbsentReason	C	0..1	CodeableConcept	Why the component result is missing Binding: DataAbsentReason (extensible): Codes specifying why the result (Observation.value[x]) is missing.
interpretation		0..*	CodeableConcept	High, low, normal, etc. Binding: ObservationInterpretationCodes (extensible): Codes identifying interpretations of observations.
referenceRange		0..*	See referenceRange (Observation)	Provides guide for interpretation of component result
component:PharmacologicalTestActiveSubstanceInEyedrops	Σ	0..1	BackboneElement	Component results
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
code	Σ	1..1	CodeableConcept	Type of component observation (code / type) Binding: LOINCCodes (example): Codes identifying names of simple observations. Fixed Value: As shown
id		0..0	string	Unique id for inter-element referencing
extension		0..0	Extension	Additional content defined by implementations
coding		1..1	Coding	Code defined by a terminology system Fixed Value: (complex)
id		0..0	string	Unique id for inter-element referencing
extension		0..0	Extension	Additional content defined by implementations
system		1..1	uri	Identity of the terminology system Fixed Value: http://snomed.info/sct
version		0..0	string	Version of the system - if relevant
code		1..1	code	Symbol in syntax defined by the system Fixed Value: 410942007
display		1..1	string	Representation defined by the system Fixed Value: Drug or medicament (substance)
userSelected		0..0	boolean	If this coding was chosen directly by the user
text		0..0	string	Plain text representation of the concept
value[x]	Σ	0..1		Actual component result Binding: Pupil Testing Active Substances (preferred): Valueset of active substances typically used in pharmacological pupil testing
valueCodeableConcept			CodeableConcept
valueString			string
dataAbsentReason	C	0..1	CodeableConcept	Why the component result is missing Binding: DataAbsentReason (extensible): Codes specifying why the result (Observation.value[x]) is missing.
interpretation		0..*	CodeableConcept	High, low, normal, etc. Binding: ObservationInterpretationCodes (extensible): Codes identifying interpretations of observations.
referenceRange		0..*	See referenceRange (Observation)	Provides guide for interpretation of component result
component:PharmacologicalTestEyedropConcentration	Σ	0..1	BackboneElement	Component results
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
code	Σ	1..1	CodeableConcept	Type of component observation (code / type) Binding: LOINCCodes (example): Codes identifying names of simple observations. Fixed Value: As shown
id		0..0	string	Unique id for inter-element referencing
extension		0..0	Extension	Additional content defined by implementations
coding		1..1	Coding	Code defined by a terminology system Fixed Value: (complex)
id		0..0	string	Unique id for inter-element referencing
extension		0..0	Extension	Additional content defined by implementations
system		1..1	uri	Identity of the terminology system Fixed Value: http://snomed.info/sct
version		0..0	string	Version of the system - if relevant
code		1..1	code	Symbol in syntax defined by the system Fixed Value: 702942001
display		1..1	string	Representation defined by the system Fixed Value: Concentration
userSelected		0..0	boolean	If this coding was chosen directly by the user
text		0..0	string	Plain text representation of the concept
value[x]	Σ	0..1	Quantity	Actual component result
dataAbsentReason	C	0..1	CodeableConcept	Why the component result is missing Binding: DataAbsentReason (extensible): Codes specifying why the result (Observation.value[x]) is missing.
interpretation		0..*	CodeableConcept	High, low, normal, etc. Binding: ObservationInterpretationCodes (extensible): Codes identifying interpretations of observations.
referenceRange		0..*	See referenceRange (Observation)	Provides guide for interpretation of component result
Documentation for this format

Terminology Bindings

Path	Conformance	ValueSet / Code	URI
Observation.language	preferred	CommonLanguages http://hl7.org/fhir/ValueSet/languages from the FHIR Standard Additional Bindings Purpose AllLanguages Max Binding
Observation.status	required	ObservationStatus http://terminology.hl7.org/uv/eyecare/ValueSet/observation-final-status from this IG
Observation.category	preferred	ObservationCategoryCodes http://hl7.org/fhir/ValueSet/observation-category from the FHIR Standard
Observation.category:ophthalCategory	preferred	ObservationCategoryCodes http://hl7.org/fhir/ValueSet/observation-category from the FHIR Standard
Observation.code	example	Fixed Value: LOINC Code LP73214-6("Pupil diameter") http://hl7.org/fhir/ValueSet/observation-codes from the FHIR Standard
Observation.value[x].comparator	required	QuantityComparator http://hl7.org/fhir/ValueSet/quantity-comparator|4.0.1 from the FHIR Standard
Observation.dataAbsentReason	extensible	DataAbsentReason http://hl7.org/fhir/ValueSet/data-absent-reason from the FHIR Standard
Observation.interpretation	extensible	ObservationInterpretationCodes http://hl7.org/fhir/ValueSet/observation-interpretation from the FHIR Standard
Observation.bodySite	required	​https://larfuma.github.io/fhir-eyecare-ig/ValueSet-right-left-both-eyes https://larfuma.github.io/fhir-eyecare-ig/ValueSet-right-left-both-eyes
Observation.bodySite.coding	required	ValueSet-right-left-eyes https://larfuma.github.io/fhir-eyecare-ig/ValueSet-right-left-eyes.html from this IG
Observation.method	example	ObservationMethods http://hl7.org/fhir/ValueSet/observation-methods from the FHIR Standard
Observation.referenceRange.type	preferred	ObservationReferenceRangeMeaningCodes http://hl7.org/fhir/ValueSet/referencerange-meaning from the FHIR Standard
Observation.referenceRange.appliesTo	example	ObservationReferenceRangeAppliesToCodes http://hl7.org/fhir/ValueSet/referencerange-appliesto from the FHIR Standard
Observation.component.code	example	LOINCCodes (a valid code from LOINC) http://hl7.org/fhir/ValueSet/observation-codes from the FHIR Standard
Observation.component.dataAbsentReason	extensible	DataAbsentReason http://hl7.org/fhir/ValueSet/data-absent-reason from the FHIR Standard
Observation.component.interpretation	extensible	ObservationInterpretationCodes http://hl7.org/fhir/ValueSet/observation-interpretation from the FHIR Standard
Observation.component:RoomBrightness.code	example	Fixed Value: LOINC Code LP429645-7("Room brightness level during testing") http://hl7.org/fhir/ValueSet/observation-codes from the FHIR Standard
Observation.component:RoomBrightness.value[x]:valueCodeableConcept	preferred	RoomBrightnessLevels https://larfuma.github.io/fhir-eyecare-ig/ValueSet-room-brightness-levels from this IG
Observation.component:RoomBrightness.value[x]:valueQuantity.comparator	required	QuantityComparator http://hl7.org/fhir/ValueSet/quantity-comparator|4.0.1 from the FHIR Standard
Observation.component:RoomBrightness.dataAbsentReason	extensible	DataAbsentReason http://hl7.org/fhir/ValueSet/data-absent-reason from the FHIR Standard
Observation.component:PupilLuminance.code	example	Fixed Value: SNOMED-CT Code 27073006("Luminance") http://hl7.org/fhir/ValueSet/observation-codes from the FHIR Standard
Observation.component:PupilLuminance.value[x].comparator	required	QuantityComparator http://hl7.org/fhir/ValueSet/quantity-comparator|4.0.1 from the FHIR Standard
Observation.component:PupilLuminance.dataAbsentReason	extensible	DataAbsentReason http://hl7.org/fhir/ValueSet/data-absent-reason from the FHIR Standard
Observation.component:PharmacologicalTestDurationSinceAdministration.code	example	LOINCCodes (a valid code from LOINC) http://hl7.org/fhir/ValueSet/observation-codes from the FHIR Standard
Observation.component:PharmacologicalTestDurationSinceAdministration.value[x].comparator	required	QuantityComparator http://hl7.org/fhir/ValueSet/quantity-comparator|4.0.1 from the FHIR Standard
Observation.component:PharmacologicalTestDurationSinceAdministration.dataAbsentReason	extensible	DataAbsentReason http://hl7.org/fhir/ValueSet/data-absent-reason from the FHIR Standard
Observation.component:PharmacologicalTestDurationSinceAdministration.interpretation	extensible	ObservationInterpretationCodes http://hl7.org/fhir/ValueSet/observation-interpretation from the FHIR Standard
Observation.component:PharmacologicalTestActiveSubstanceInEyedrops.code	example	Fixed Value: SNOMED-CT Code 410942007("Drug or medicament (substance)") http://hl7.org/fhir/ValueSet/observation-codes from the FHIR Standard
Observation.component:PharmacologicalTestActiveSubstanceInEyedrops.value[x]	preferred	PupiTestingActiveSubstances https://larfuma.github.io/fhir-eyecare-ig/ValueSet-pupi-testing-active-substances from this IG
Observation.component:PharmacologicalTestActiveSubstanceInEyedrops.dataAbsentReason	extensible	DataAbsentReason http://hl7.org/fhir/ValueSet/data-absent-reason from the FHIR Standard
Observation.component:PharmacologicalTestActiveSubstanceInEyedrops.interpretation	extensible	ObservationInterpretationCodes http://hl7.org/fhir/ValueSet/observation-interpretation from the FHIR Standard
Observation.component:PharmacologicalTestEyedropConcentration.code	example	Fixed Value: SNOMED-CT Code 702942001("Concentration") http://hl7.org/fhir/ValueSet/observation-codes from the FHIR Standard
Observation.component:PharmacologicalTestEyedropConcentration.dataAbsentReason	extensible	DataAbsentReason http://hl7.org/fhir/ValueSet/data-absent-reason from the FHIR Standard
Observation.component:PharmacologicalTestEyedropConcentration.interpretation	extensible	ObservationInterpretationCodes http://hl7.org/fhir/ValueSet/observation-interpretation from the FHIR Standard

Constraints

Id	Grade	Path(s)	Details	Requirements
dom-2	error	Observation	If the resource is contained in another resource, it SHALL NOT contain nested Resources : contained.contained.empty()
dom-3	error	Observation	If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource : contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()
dom-4	error	Observation	If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated : contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()
dom-5	error	Observation	If a resource is contained in another resource, it SHALL NOT have a security label : contained.meta.security.empty()
dom-6	best practice	Observation	A resource should have narrative for robust management : text.`div`.exists()
ele-1	error	**ALL** elements	All FHIR elements must have a @value or children : hasValue() or (children().count() > id.count())
ext-1	error	**ALL** extensions	Must have either extensions or value[x], not both : extension.exists() != value.exists()
inv-pharmacological-test-partOf-warning	warning	Observation	Include a reference to MedicationAdministration in partOf when PharmacologicalTestActiveSubstanceInEyedrops is present. : component.where(code.coding.code = '410942007').exists() implies partOf.exists()
obs-3	error	Observation.referenceRange	Must have at least a low or a high or text : low.exists() or high.exists() or text.exists()
obs-6	error	Observation	dataAbsentReason SHALL only be present if Observation.value[x] is not present : dataAbsentReason.empty() or value.empty()
obs-7	error	Observation	If Observation.code is the same as an Observation.component.code then the value element associated with the code SHALL NOT be present : value.empty() or component.code.where(coding.intersect(%resource.code.coding).exists()).empty()

Summary

Mandatory: 2 elements
Fixed: 17 elements
Prohibited: 5 elements

Structures

This structure refers to these other structures:

• Unable to summarise profile https://larfuma.github.io/fhir-eyecare-ig/StructureDefinition-pupil-comparison (no profile found)

Slices

This structure defines the following Slices:

• The element 1 is sliced based on the value of Observation.component
• The element 1 is sliced based on the value of Observation.component.value[x]

Name	Flags	Card.	Type	Description & Constraints
Observation	C	0..*	ObservationBase	Measurements and simple assertions inv-pharmacological-test-partOf-warning: Include a reference to MedicationAdministration in partOf when PharmacologicalTestActiveSubstanceInEyedrops is present.
partOf		0..*	Reference(https://larfuma.github.io/fhir-eyecare-ig/StructureDefinition-pupil-comparison)	Reference for Pharmacological Testing
code		1..1	CodeableConcept	Type of observation (code / type) Fixed Value: As shown
coding		1..1	Coding	Code defined by a terminology system Fixed Value: (complex)
system		1..1	uri	Identity of the terminology system Fixed Value: http://loinc.org
code		1..1	code	Symbol in syntax defined by the system Fixed Value: LP73214-6
display		1..1	string	Representation defined by the system Fixed Value: Pupil diameter
value[x]		1..1	Quantity	Actual result
unit		0..1	string	mm Fixed Value: mm
system		0..1	uri	System that defines coded unit form Fixed Value: http://unitsofmeasure.org
code		0..1	code	Coded form of the unit Fixed Value: mm
note		0..0
bodySite		1..1	CodeableConcept	​Observed body part Binding: https://larfuma.github.io/fhir-eyecare-ig/ValueSet-right-left-both-eyes (required)
coding		0..*	Coding	Code defined by a terminology system Binding: ValueSet-right-left-eyes (required): Valueset constrained to either the right or left eye
Slices for component		0..*	BackboneElement	Component results Slice: Unordered, Open by value:code
component:RoomBrightness		0..1	BackboneElement	Component results
code		1..1	CodeableConcept	Type of component observation (code / type) Fixed Value: As shown
coding		1..1	Coding	Code defined by a terminology system Fixed Value: (complex)
system		1..1	uri	Identity of the terminology system Fixed Value: http://loinc.org
code		1..1	code	Symbol in syntax defined by the system Fixed Value: LP429645-7
display		1..1	string	Representation defined by the system Fixed Value: Room brightness level during testing
Slices for value[x]		0..1		Actual component result Slice: Unordered, Open by type:$this
valueQuantity			Quantity
valueCodeableConcept			CodeableConcept
value[x]:valueCodeableConcept		0..1	CodeableConcept	Actual component result Binding: Room Brightness Levels (preferred): Room Brightness levels
value[x]:valueQuantity		0..1	Quantity	Luminance
unit		0..1	string	Room Illuminance Fixed Value: lux
system		0..1	uri	System that defines coded unit form Fixed Value: http://unitsofmeasure.org
code		0..1	code	Lux Fixed Value: lx
interpretation		0..0
referenceRange		0..0
component:PupilLuminance		0..1	BackboneElement	Component results
code		1..1	CodeableConcept	Type of component observation (code / type) Fixed Value: As shown
coding		1..1	Coding	Code defined by a terminology system Fixed Value: (complex)
system		1..1	uri	Identity of the terminology system Fixed Value: http://snomed.info/sct
code		1..1	code	Symbol in syntax defined by the system Fixed Value: 27073006
display		1..1	string	Representation defined by the system Fixed Value: Luminance
value[x]		0..1	Quantity	Actual component result
unit		0..1	string	candela per square meter Fixed Value: cd/m2
system		0..1	uri	System that defines coded unit form Fixed Value: http://unitsofmeasure.org
code		0..1	code	Coded form of the unit Fixed Value: cd/m2
interpretation		0..0
referenceRange		0..0
component:PharmacologicalTestDurationSinceAdministration		0..1	BackboneElement	Component results
value[x]		0..1	Quantity	Actual component result
unit		0..1	string	Unit representation Fixed Value: minutes
system		0..1	uri	System that defines coded unit form Fixed Value: unitsofmeasure.org
code		0..1	code	Coded form of the unit Fixed Value: min
component:PharmacologicalTestActiveSubstanceInEyedrops		0..1	BackboneElement	Component results
code		1..1	CodeableConcept	Type of component observation (code / type) Fixed Value: As shown
coding		1..1	Coding	Code defined by a terminology system Fixed Value: (complex)
system		1..1	uri	Identity of the terminology system Fixed Value: http://snomed.info/sct
code		1..1	code	Symbol in syntax defined by the system Fixed Value: 410942007
display		1..1	string	Representation defined by the system Fixed Value: Drug or medicament (substance)
value[x]		0..1		Actual component result Binding: Pupil Testing Active Substances (preferred): Valueset of active substances typically used in pharmacological pupil testing
valueCodeableConcept			CodeableConcept
valueString			string
component:PharmacologicalTestEyedropConcentration		0..1	BackboneElement	Component results
code		1..1	CodeableConcept	Type of component observation (code / type) Fixed Value: As shown
coding		1..1	Coding	Code defined by a terminology system Fixed Value: (complex)
system		1..1	uri	Identity of the terminology system Fixed Value: http://snomed.info/sct
code		1..1	code	Symbol in syntax defined by the system Fixed Value: 702942001
display		1..1	string	Representation defined by the system Fixed Value: Concentration
value[x]		0..1	Quantity	Actual component result
Documentation for this format

Terminology Bindings (Differential)

Path	Conformance	ValueSet	URI
Observation.bodySite	required	​https://larfuma.github.io/fhir-eyecare-ig/ValueSet-right-left-both-eyes https://larfuma.github.io/fhir-eyecare-ig/ValueSet-right-left-both-eyes
Observation.bodySite.coding	required	ValueSet-right-left-eyes https://larfuma.github.io/fhir-eyecare-ig/ValueSet-right-left-eyes.html from this IG
Observation.component:RoomBrightness.value[x]:valueCodeableConcept	preferred	RoomBrightnessLevels https://larfuma.github.io/fhir-eyecare-ig/ValueSet-room-brightness-levels from this IG
Observation.component:PharmacologicalTestActiveSubstanceInEyedrops.value[x]	preferred	PupiTestingActiveSubstances https://larfuma.github.io/fhir-eyecare-ig/ValueSet-pupi-testing-active-substances from this IG

Constraints

Id	Grade	Path(s)	Details	Requirements
inv-pharmacological-test-partOf-warning	warning	Observation	Include a reference to MedicationAdministration in partOf when PharmacologicalTestActiveSubstanceInEyedrops is present. : component.where(code.coding.code = '410942007').exists() implies partOf.exists()